The action gets under way this evening with Motherwell v Morton (live on BT Sport) and Dundee United v Cowdenbeath.
Saturday's games include Hibernian v Alloa Athletic at Easter Road, East Kilbride v St Mirren at K-Park and Ayr United v Falkirk at Somerset Park.
On Sunday, St Johnstone host Group B leaders Ross County at McDiarmid Park, live on BT Sport at 3.00pm.