Celtic are already through to the last 32 and will be seeded in the draw, which takes place at 12 noon on Monday. Neil Lennon's men are in Romania to play CFR Cluj, kick-off 5.55pm, and are aiming to continue their unbeaten record in Group E.
Rangers go into matchday six at the top of Group G and knowing that a draw against Young Boys at Ibrox, kick-off 8.00pm, will see them through to the knock-out phase. In a tight section, Young Boys, Porto and Feyenoord are all in contention to progress.
Both of this evening's games are live on BT Sport.