Henderson has bagged 30 goals in 34 Ladbrokes League 2 games and is two clear of Raith Rovers forward Kevin Nisbet, who has netted 28 times in Ladbrokes League 1.
Third on the list is Ayr United forward Lawrence Shankland, with 23 goals in the Ladbrokes Championship.
Leading scorer in the Ladbrokes Premiership is Rangers striker Alfredo Morelos, who has scored 17 league goals.