Celtic require a maximum of five more points to clinch the title so could be crowned champions on Sunday if they beat Hibernian at Easter Road – live on Sky Sports at 12.30pm – and Rangers drop points at Tynecastle on Saturday, live on Sky Sports at 12 noon.
The other top-six game sees Kilmarnock and Aberdeen meet at Rugby Park in an important match in the battle for a European spot, with the teams level on 58 points.
Bottom club Dundee make the short journey to McDiarmid Park to play St Johnstone while St Mirren, who occupy the relegation play-off place, travel to Livingston and Hamilton Accies host Motherwell in the Lanarkshire derby.