The action gets under way on Saturday when Aberdeen host Rangers at Pittodrie, live on Sky Sports with a 12.30pm kick-off.
Dundee United mark their Premiership return with a home game against St Johnstone - both teams have new managers in Micky Mellon and Callum Davidson.
Also on Saturday, Hibernian welcome Kilmarnock to Easter Road and St Mirren go up against Livingston in Paisley.
Celtic begin their title defence on Sunday when Hamilton Accies are the visitors to Celtic Park, live on Sky Sports at 4.30pm.
The final fixture of the opening weekend is in Dingwall on Monday evening when Ross County host Motherwell, live on Sky Sports at 7.45pm.