Leaders Rangers head for Livingston while second-placed Hibernian are away to bottom club Alloa and there's Friday night football in Paisley.
St Mirren (8) v Morton (4) - Friday, 7.45pm (BBC ALBA)
St Mirren are yet to win at home, with two draws and five defeats.
St Mirren are on a run of three straight defeats.
Morton's away record is three wins, one draw and four defeats.
Morton have won four games in a row after losing the previous four.
It was 0-0 when the sides met at Cappielow back in August.
Alloa Athletic (10) v Hibernian (2) - Saturday, 3.00pm
Alloa have picked up just one point from six home games so far.
Alloa have lost their last five games and are five points adrift at the bottom.
Hibernian are on a run of seven straight wins and are unbeaten in 11.
Hibernian have won five and lost two of their seven away games.
Hibernian won 3-0 when the teams met at Easter Road in mid-September.
Dumbarton (9) v Raith Rovers (5) - Saturday, 3.00pm
Dumbarton have won two and lost five of their seven home games.
Dumbarton have taken just one point from the last four matches.
Raith Rovers have won two and lost four of their six away games.
Raith Rovers have lost three on the trot after winning the previous five.
It was 1-0 to Raith Rovers when the sides met at Stark's Park in September.
Livingston (7) v Rangers (1) - Saturday, 3.00pm
Livingston have lost five of their six home games this season.
Livingston were beaten 2-1 by Hibernian at Easter Road on Tuesday.
Rangers have won five and lost one of their six away games.
Rangers beat Alloa 4-0 at Ibrox in their last outing a fortnight ago.
Rangers saw off Livingston 3-0 at Ibrox when the sides met in September.
Queen of the South (6) v Falkirk (3) - Saturday, 3.00pm
Queen of the South have won three, drawn one and lost four at home.
Queen of the South were beaten 2-0 away to Morton last weekend.
Falkirk are on a run of four straight victories.
Falkirk's away record is four wins, two draws and one defeat.
It was 0-0 when the teams met at the Falkirk Stadium in September.